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Posts tagged “stem cells”

Scientists discover new stem cells, which could help to repair and regenerate teeth

Scientists at Plymouth University have made an exciting discovery, which could make regenerating the teeth a possibility in the future. 

A team of researchers from the university has discovered a new group of stem cells and the gene, which activates it. This group is responsible for the formation of skeletal and tooth tissue, most notably dentin. Dentin is the hard tissue that protects the nerves, the blood vessels and the pulp tissue, and it is found beneath the enamel surface. At the moment, when a tooth is damaged, it can only be restored, usually by means of a crown or a filling. With this new stem cell research, it could be possible to regenerate damaged tissue and effectively grow new teeth. 

Lead researcher, Dr Bing Hu, said that the importance and value of stem cells is well-documented, but to fully understand the capabilities of stem cells, it’s crucial to learn how they work. The group discovered new stem cells, as well as the gene that activates them, known as Dlkl. By finding the stem cells and the gene, and investigating how Dlkl is involved in stem cell regeneration, the team has made major strides to understand stem cell regeneration. The research can now form a base for further exploration and to determine how to develop lab-based techniques for human use. 

Co-author of the study, Prof Christopher Tredwin, head of the Peninsula Dental School at Plymouth University, said that the research will hopefully provide dental patients with more effective, affordable solutions for tooth problems and injuries in the future. 

Dental injuries and diseases are commonplace in the UK, with 170 extraction procedures carried out on under 18’s every day.

The findings have been published in the Nature Communications journal. 

Stained and yellowing teeth can cost you far more than just your confidence.

Researchers in the US are urging parents to keep their children’s baby teeth to combat potentially deadly diseases later in life.

Scientists from the United States National Center for Biotechnology claim that the stem cells in baby teeth are likely to be in better condition than those found in adult teeth, which may have been exposed to environmental hazards. Stem cells play a valuable role in the regeneration of new cells, and could help to save lives, according to the research team. It is thought that in some cases, using stem cells from milk teeth could eliminate the need to try and obtain stem cells from the bone marrow, which is a more complex process.

Although using stem cells from milk teeth is a relatively new concept, researchers believe that it could become much more commonplace in the near future. Stem cells could be used to treat some forms of cancer and to try and prevent heart attacks, and it’s also possible for the cells to facilitate bone growth, to regenerate tissue in the liver and eyes and to treat diabetes. Cells can be harvested from baby teeth up to 10 years after the tooth has been lost.

A trial in China revealed that stem cells taken from milk teeth helped to restore feeling and sensation in damaged adult teeth. Songtao Shi, from the University of Pennsylvania, which was involved in the study, explained that the treatment gave patients the ability to feel again, for example, to experience hot and cold. The university team is now planning to work on a trial that determines how using stem cells from a child can impact other people.

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